IGFL3 Protein (AA 25-140) (DYKDDDDK Tag)
(1 reference)-
- Target See all IGFL3 products
- IGFL3 (IGF-Like Family Member 3 (IGFL3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-140
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFL3 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse IGFL (aa 25-140) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
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IGF-Like Family Member 3 (IGFL3) (AA 25-125) protein (His tag)
Crystallography grade IGFL3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
IGF-Like Family Member 3 (IGFL3) (AA 25-140) protein (His tag)Crystallography grade IGFL3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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: "Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1." in: The Journal of biological chemistry, Vol. 286, Issue 21, pp. 18969-81, (2011) (PubMed).
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: "Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1." in: The Journal of biological chemistry, Vol. 286, Issue 21, pp. 18969-81, (2011) (PubMed).
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- Target
- IGFL3 (IGF-Like Family Member 3 (IGFL3))
- Alternative Name
- IGFL (IGFL3 Products)
- Synonyms
- UNQ483 Protein, Gm580 Protein, Igfl Protein, Rprc483 Protein, Ceacam12 Protein, IGF like family member 3 Protein, IGF-like family member 3 Protein, IGFL3 Protein, Igfl3 Protein
- Background
- Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
- Molecular Weight
- ~12kDa (SDS-PAGE)
- UniProt
- Q6B9Z0
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