EGLN1 Protein (AA 1-222) (His tag)

Catalog No. ABIN1474871

Product Details

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Protein Type: Recombinant

Protein Characteristics: AA 1-222

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This EGLN1 protein is labelled with His tag.

Application: ELISA

Sequence: MNKHGICVVD DFLGRETGQQ IGDEVRALHD TGKFTDGQLV SQKSDSSKDI RGDKITWIEG KEPGCETIGL LMSSMDDLIR HCSGKLGNYR INGRTKAMVA CYPGNGTGYV RHVDNPNGDG RCVTCIYYLN KDWDAKVSGG ILRIFPEGKA QFADIEPKFD RLLFFWSDRR NPHEVQPAYA TRYAITVWYF DADERARAKV KYLTGEKGVR VELKPNSVSK DV

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))

Alternative Name: Egl nine homolog 1 (Egln1) (EGLN1 Products)

Synonyms: EGLN1 Protein, egln2 Protein, phd2 Protein, zgc:92314 Protein, AI503754 Protein, C1orf12 Protein, HIF-PH2 Protein, HPH-2 Protein, Hif-p4h-2 Protein, ORF13 Protein, Phd2 Protein, SM-20 Protein, PHD-2 Protein, PHD2 Protein, ECYT3 Protein, HIFPH2 Protein, HPH2 Protein, SM20 Protein, ZMYND6 Protein, egl nine homolog 1 (C. elegans) Protein, egl-9 family hypoxia inducible factor 1 Protein, egl-9 family hypoxia-inducible factor 1 S homeolog Protein, egl-9 family hypoxia-inducible factor 1b Protein, egl-9 family hypoxia-inducible factor 1 Protein, EGLN1 Protein, egln1.S Protein, egln1b Protein, Egln1 Protein

Background: Recommended name: Egl nine homolog 1.
EC= 1.14.11.29.
Alternative name(s): Hypoxia-inducible factor prolyl hydroxylase 2.
Short name= HIF-PH2.
Short name= HIF-prolyl hydroxylase 2.
Short name= HPH-2 Prolyl hydroxylase domain-containing protein 2.
Short name= PHD2

UniProt: P59722

Pathways: cAMP Metabolic Process, Warburg Effect