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ANG Protein (AA 26-147) (His tag)

ANG Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Catalog No. ABIN1046529
  • Target See all ANG Proteins
    ANG (Angiogenin (ANG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 26-147
    Origin
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 16
    • 13
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ANG protein is labelled with His tag.
    Application
    SDS-PAGE (SDS), ELISA
    Sequence
    DNSRYTHFLT QHYDAKPQGR DDRYCESIMR RRGLTSPCKD INTFIHGNKR SIKAICENKN GNPHRENLRI SKSSFQVTTC KLHGGSPWPP CQYRATAGFR NVVVACENGL PVHLDQSIFR RP-
    Characteristics
    May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
    Purity
    90 %
    Top Product
    Discover our top product ANG Protein
  • Comment

    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • Zhang, Rosenberg: "Diversifying selection of the tumor-growth promoter angiogenin in primate evolution." in: Molecular biology and evolution, Vol. 19, Issue 4, pp. 438-45, (2002) (PubMed).

    Kurachi, Davie, Strydom, Riordan, Vallee: "Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor." in: Biochemistry, Vol. 24, Issue 20, pp. 5494-9, (1986) (PubMed).

  • Target
    ANG (Angiogenin (ANG))
    Alternative Name
    Angiogenin (ANG Products)
    Synonyms
    ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, ANG Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, ANG1 Protein, angiogenin Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ribonuclease A family member k6 Protein, ANG Protein, Ang Protein, RNASE6 Protein
    Background
    Synonyms: Ribonuclease 5,Nase 5
    Molecular Weight
    18 kDa
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