ROCK1 Protein (AA 1-441) (His tag)

Catalog No. ABIN1642467

Product Details

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Protein Type: Recombinant

Protein Characteristics: AA 1-441

Origin: Cow

Source: Yeast

Purification tag / Conjugate: This ROCK1 protein is labelled with His tag.

Application: ELISA

Sequence: NSKSQMDKDY YQLQAVLEAE RRDRGHDSEK IGDLQARITS LQEEVKHLKH NLERVEGERK EAQDMLNHSE KEKNNLEIDL NYKLKSLQQR LEQEVNEHKV TKARLTDKHQ SIEEAKSVAM CEMEKKLKEE RDAREKAENR VVQIEKQCSM LDVDLKQSQQ KLEHLIENKD RMEDEVKNLT LQLEQESNKR LLLQNELKTQ AFEADNLKGL EKQMKQEINT LLEAKRLLEF ELAQLTKQYR GNEGQMRELQ DQLEAEQYFS TLYKTQVKEL KEEIEEKNRE NLKKIQELQS EKETLATQLD LAETKAESEQ LARGLLEEQY FELTQESKKA ASRNRQEITD KDHTLSRLEE TNSMLTKDIE LLRKENEELT DKMRKAEEEY KLKKEEEINI LKAAFEKNIN TERTLKTQAV NKLAEIMNRK DFKIDRKKAN TQDLRKKKKK K

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Alternative Name: Rho-associated protein kinase 1 (ROCK1) (ROCK1 Products)

Synonyms: LOC100229794 Protein, CG9774 Protein, DROK Protein, DRhk Protein, DRok Protein, Dmel\\CG9774 Protein, Drok Protein, ROCK Protein, ROCK-1 Protein, ROCK1 Protein, ROK Protein, ROKalpha/beta Protein, Rhk Protein, RhoK Protein, Rock Protein, Rok Protein, dROK Protein, dRok Protein, drok Protein, 1110055K06Rik Protein, Rock-I Protein, P160Rock Protein, ROCK-I Protein, P160ROCK Protein, p160ROCK Protein, Rho associated coiled-coil containing protein kinase 1 Protein, Rho kinase Protein, Rho-associated coiled-coil containing protein kinase 1 Protein, Rho-associated, coiled-coil containing protein kinase 1 Protein, ROCK1 Protein, Rok Protein, Rock1 Protein, rock1 Protein

Background: Recommended name: Rho-associated protein kinase 1.
EC= 2.7.11.1.
Alternative name(s): Rho-associated, coiled-coil-containing protein kinase 1 Rho-associated, coiled-coil-containing protein kinase I.
Short name= ROCK-I p160 ROCK-1.
Short name= p160ROCK

UniProt: Q8MIT6

Pathways: Microtubule Dynamics, WNT Signaling, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling