HLA-DRB1 Protein (AA 30-227) (His tag)

Catalog No. ABIN1660811

Product Details

Target: HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))

Protein Type: Recombinant

Protein Characteristics: AA 30-227

Origin: Dog

Source: Yeast

Purification tag / Conjugate: This HLA-DRB1 protein is labelled with His tag.

Application: ELISA

Sequence: R DTPPHFLEVA KSECYFTNGT ERVRFVERYI HNREEFVRFD SDVGEFRAVT ELGRPVAESW NGQKEILEQE RATVDTYCRH NYGVIESFTV QRRVEPTVTV YPTKTQTLQH HNLLVCSVNG FYPGHIEVRW LRNGQEEEAG VVSTGLIRNG DWTFQILVML EIVPQSGEVY TCQVEHPSLT SPVTVEWRAQ SDSAQSK

Specificity: Canis familiaris (Dog) (Canis lupus familiaris)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))

Alternative Name: DLA class II histocompatibility antigen, DR-1 beta chain (HLA-DRB1 Products)

Synonyms: MGC108235 Protein, DRB1 Protein, DRw10 Protein, HLA-DR1B Protein, HLA-DRB Protein, SS1 Protein, major histocompatibility complex, class II, DR beta 1 Protein, hla-drb1 Protein, HLA-DRB1 Protein

Background: Recommended name: DLA class II histocompatibility antigen, DR-1 beta chain

UniProt: P18470

Pathways: TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Cancer Immune Checkpoints