CD200R1 Protein (AA 27-266) (His tag)

Catalog No. ABIN1691053

This Recombinant CD200R1 protein is produced in Human Cells.

Quick Overview for CD200R1 Protein (AA 27-266) (His tag) (ABIN1691053)

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 27-266

Purification tag / Conjugate: This CD200R1 protein is labelled with His tag.

Purpose: Recombinant Human CD200 Receptor 1/CD200R1 (C-6His)

Sequence: AAQPNNSLML QTSKENHALA SSSLCMDEKQ ITQNYSKVLA EVNTSWPVKM ATNAVLCCPP IALRNLIIIT WEIILRGQPS CTKAYKKETN ETKETNCTDE RITWVSRPDQ NSDLQIRTVA ITHDGYYRCI MVTPDGNFHR GYHLQVLVTP EVTLFQNRNR TAVCKAVAGK PAAHISWIPE GDCATKQEYW SNGTVTVKST CHWEVHNVST VTCHVSHLTG NKSLYIELLP VPGAKKSAKL VDHHHHHH

Characteristics: Recombinant Human CD200 Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala27-Leu266 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Storage: 4 °C,-20 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 weeks

Target Details

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Alternative Name: CD200 R1

Background: Alternative Names: Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, CD200R1, CD200R, CRTR2, MOX2R, OX2RRecombinant Human CD200 R1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Met29-Leu325) of Human CD200 R1 fused with a polyhistidine tag at the C-terminus.
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.

Molecular Weight: 25.22 kDa

UniProt: Q8TD46