cDNA Sequence AF251705 (AF251705) (AA 21-183) protein (Fc Tag)
AF251705
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- Target See all cDNA Sequence AF251705 (AF251705) products
- cDNA Sequence AF251705 (AF251705)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-183
- Origin
- Human
- Source
- Human Cells
- Purification tag / Conjugate
- Fc Tag
- Purpose
- Recombinant Human Leukocyte Mono Ig-Like Receptor 2/LMIR2/CD300C (C-Fc)
- Sequence
- GYFPLSHPMT VAGPVGGSLS VQCRYEKEHR TLNKFWCRPP QILRCDKIVE TKGSAGKRNG RVSIRDSPAN LSFTVTLENL TEEDAGTYWC GVDTPWLRDF HDPIVEVEVS VFPAGTTTAS SPQSSMGTSG PPTKLPVHTW PSVTRKDSPE PSPHPGSLFS NVRVDDIEGR MDEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGK
- Characteristics
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Recombinant Human Leukocyte Mono Ig-Like Receptor 2/LMIR2/CD300C (C-Fc)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- cDNA Sequence AF251705 (AF251705)
- Alternative Name
- Leukocyte Mono Ig-Like Receptor 2 (AF251705 Products)
- Synonyms
- CLM4 Protein, Cd300c Protein, Cd300d Protein, DIgR1 Protein, Igsf7 Protein, Lmir2 Protein, MAIR-II Protein, CD300C molecule 2 Protein, Cd300c2 Protein
- Background
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Recombinant Human CD300C is produced by our mammalian expression system. The target protein is expressed with sequence (Gly21-Arg183) of Human CD300Cfused with a FC tag at the C-terminus.
CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-α and IFN-α secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown. - Molecular Weight
- 44.9 kDa
- UniProt
- Q08708
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