C1QBP Protein (AA 74-282) (His tag)
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- Target See all C1QBP Proteins
- C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 74-282
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This C1QBP protein is labelled with His tag.
- Purpose
- Recombinant Human C1QBP/HABP1 (C-6His)
- Sequence
- MLHTDGDKAF VDFLSDEIKE ERKIQKHKTL PKMSGGWELE LNGTEAKLVR KVAGEKITVT FNINNSIPPT FDGEEEPSQG QKVEEQEPEL TSTPNFVVEV IKNDDGKKAL VLDCHYPEDE VGQEDEAESD IFSIREVSFQ STGESEWKDT NYTLNTDSLD WALYDHLMDF LADRGVDNTF ADELVELSTA LEHQEYITFL EDLKSFVKSQ LEHHHHHH
- Characteristics
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Recombinant Human C1QBP/HABP1 (C-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product C1QBP Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 20 % Glycerol, 1 mM DTT, pH 7.5.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))
- Alternative Name
- Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial/C1QBP (C1QBP Products)
- Synonyms
- SF2 Protein, X38k Protein, gC1qR Protein, C1QBP Protein, GC1QBP Protein, HABP1 Protein, SF2p32 Protein, gC1Q-R Protein, p32 Protein, AA407365 Protein, AA986492 Protein, D11Wsu182e Protein, P32 Protein, gC1qBP Protein, Habp1 Protein, complement C1q binding protein Protein, complement component 1, q subcomponent binding protein S homeolog Protein, complement component 1, q subcomponent binding protein Protein, C1QBP Protein, c1qbp.S Protein, LOC100227158 Protein, C1qbp Protein
- Background
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Recombinant Human Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial/C1QBP is produced with our E. coli expression system. The target protein is expressed with sequence (Leu74-Gln282) of Human C1QBP fused with a 6His tag at the C-terminus.
Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells. - Molecular Weight
- 24.9 kDa
- UniProt
- Q07021
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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