TFAM Protein (AA 1-246) (GST tag)

Catalog No. ABIN1989795

Product Details

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Protein Type: Recombinant

Protein Characteristics: AA 1-246

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This TFAM protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose: TFAM (Human) Recombinant Protein (P01)

Sequence: MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK YGAEEC

Characteristics: Human TFAM full-length ORF (BAG35455.1, 1 a.a. - 246 a.a.) recombinant protein with GST tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

Target Details

Target: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Alternative Name: TFAM (TFAM Products)

Synonyms: tcf6 Protein, mttf1 Protein, mttfa Protein, tcf6l1 Protein, tcf6l2 Protein, tcf6l3 Protein, mttfa-A Protein, xl-mtTFA Protein, MGC153358 Protein, zgc:153358 Protein, MTTF1 Protein, MTTFA Protein, TCF6 Protein, TCF6L1 Protein, TCF6L2 Protein, TCF6L3 Protein, AI661103 Protein, Hmgts Protein, mtTFA Protein, tsHMG Protein, Mttfa Protein, transcription factor A, mitochondrial Protein, transcription factor A, mitochondrial L homeolog Protein, TFAM Protein, tfam.L Protein, tfam Protein, Tfam Protein

Background: Synonyms: MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA
Gene Description: transcription factor A, mitochondrial
Gene Name: TFAM
Gene Summary: This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
GenBank: AK312558.1, BAG35455.1

Molecular Weight: 53.46 kDa (theoreatical)

Gene ID: 7019

Pathways: Chromatin Binding