IL-11 Protein (AA 23-199)
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- Target See all IL-11 (IL11) Proteins
- IL-11 (IL11) (Interleukin 11 (IL11))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 23-199
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Origin
- Mouse
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Source
- HEK-293T Cells
- Characteristics
- ED50 < 3 ng/mL, measured in a cell proliferation assay using T11 cells.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL11 Protein
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Interleukin 11 (IL11) (AA 22-199) protein (His tag)
IL11 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 11 (IL11) (Active) proteinIL11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 11 (IL11) protein (Fc Tag)IL11 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 11 (IL11) (AA 25-74) protein (GST tag)IL11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) (AA 1-199) protein (GST tag)IL11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) (AA 22-199) protein (His tag)Crystallography grade IL11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 11 (IL11) (AA 22-199) protein (His tag)Crystallography grade IL11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IL-11 (IL11) (Interleukin 11 (IL11))
- Alternative Name
- Interleukin-11(IL-11) (IL11 Products)
- Synonyms
- IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
- Background
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Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1alpha-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.
Synonyms: IL-11 - Molecular Weight
- 21 kDa, observed by reducing SDS-PAGE.
- UniProt
- P47873
- Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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