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CCL23 Protein (AA 32-494, AA 495-728)

CCL23 Origin: Human Host: CHO Cells Recombinant > 98 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018263
  • Target See all CCL23 Proteins
    CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 32-494, AA 495-728
    Origin
    • 14
    • 2
    • 1
    Human
    Source
    • 8
    • 5
    • 1
    • 1
    • 1
    CHO Cells
    Characteristics
    The EC50 value of human MPIF-1/CCL23 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 2 μg/mL.
    Alpha chain: AA 32-494, beta chain: AA 495-728
    Purity
    > 98 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product CCL23 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant humanMPIF-1/CCL23 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human MPIF-1/CCL23 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))
    Alternative Name
    MPIF-1/CCL23 (CCL23 Products)
    Synonyms
    CK-BETA-8 Protein, CKb8 Protein, Ckb-8 Protein, Ckb-8-1 Protein, MIP-3 Protein, MIP3 Protein, MPIF-1 Protein, SCYA23 Protein, hmrp-2a Protein, C-C motif chemokine 23 Protein, C-C motif chemokine ligand 23 Protein, chemokine (C-C motif) ligand 23 Protein, LOC508666 Protein, CCL23 Protein
    Background
    Myeloid progenitor inhibitory factor 1 (MPIF-1), also known as Chemokine (C-C motif) ligand 23 (CCL23) is a small cytokine belonging to the CC chemokine family.MPIF-1is predominantly expressed in lung and liver tissue, but is also found in bone marrow and placenta. It is also expressed in some cell lines of myeloid origin. It is highly chemotactic for resting T cells and monocytes and slightly chemotactic for neutrophils. MPIF-1 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. It has also been attributed to an inhibitory activity on hematopoietic progenitor cells. MPIF-1 is a ligand for the chemokine receptor CCR1.Recombinant human MPIF-1/CCL23 produced in CHO cells is a single polypeptide chain containing 99 amino acids. A fully biologically active molecule, rhMPIF-1/CCL23 has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE.
    Synonyms: MPIF-1/CCL23, Human
    Molecular Weight
    12 kDa, observed by reducing SDS-PAGE.
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