IFN omega (Active) Protein
Recombinant IFN omega protein expressed in Escherichia coli (E. coli).
Catalog No. ABIN2468552
$444.13
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Quick Overview for IFN omega (Active) Protein (ABIN2468552)
Target
IFN omega
Protein Type
Recombinant
Biological Activity
Active
Origin
Human
Source
Escherichia coli (E. coli)
Purity
< 98 % by SDS-PAGE gel and HPLC analyses.
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Sequence
- MCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS
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Characteristics
- The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is < 0.01 ng/mL, corresponding to a specific activity of > 1 x 106 units/mg.
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing IFN-omega recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IFN-omega is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- IFN omega
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Alternative Name
- IFN-omega
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Background
- IFN-omega is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-a, IFN-B, and IFN-w, signal through IFNAR-1/IFNAR-2 receptor complex, and exert anti-viral and anti-proliferative activities. IFN-omega exhibits about 75 % sequence homology with IFN-a, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-omega is a 19.9 kDa protein consisting of 172 amino acid residues.
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Gene ID
- 3467
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NCBI Accession
- NP_002168
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OMIM
- 4504605
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UniProt
- P05000
Target
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