IL-7 Protein
Quick Overview for IL-7 Protein (ABIN2468713)
Target
See all IL-7 (IL7) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MDCHIKDKDG KAFGSVLMIS INQLDKMTGT DSDCPNNEPN FFKKHLCDDT KEAAFLNRAA RKLRQFLKMN ISEEFNDHLL RVSDGTQTLV NCTSKEEKTI KEQKKNDPCF LKRLLREIKT CWNKILKGSI
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Characteristics
- The ED50 was determined by the dose - dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 106 units/mg.
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Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Interleukin 7 (IL7) (AA 26-177) protein
IL7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 7 (IL7) (AA 26-154) (Active) protein (His tag)IL7 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 7 (IL7) (AA 26-177) (Active) protein (His tag)IL7 Origin: Human Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
Interleukin 7 (IL7) (AA 26-154) protein (His tag)IL7 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 7 (IL7) (AA 26-177) protein (His-IF2DI Tag)IL7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 7 (IL7) (Active) protein (His tag)IL7 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 7 (IL7) (AA 26-177) protein (GST tag)IL7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Handling Advice
- As with any protein, exposing IL-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Storage
- -20 °C
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Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-7 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Expiry Date
- 24 months
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- IL-7 (IL7) (Interleukin 7 (IL7))
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Alternative Name
- IL-7
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Background
- IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
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Gene ID
- 25647
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NCBI Accession
- NP_037242
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OMIM
- 40254788
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UniProt
- P56478
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Pathways
- JAK-STAT Signaling
Target
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