NR1I3 Protein (His tag)
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- Target See all NR1I3 Proteins
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NR1I3 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
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Measured by the ability of the immobilized protein to support the adhesion of mouse neutrophils. When 50000 cells/well are added to CXADR coated plates (4 μg/mL and 100μL/well ), approximately 20 % - 50 % will adhere specifically after 60 minutes at 37˚,C.
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product NR1I3 Protein
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Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-59) protein (GST tag)
NR1I3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) protein (GST tag)NR1I3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) protein (Strep Tag)Crystallography grade NR1I3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-358) protein (Strep Tag)Crystallography grade NR1I3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) protein (His tag)NR1I3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-351), (partial) protein (His-SUMO Tag)NR1I3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Alternative Name
- CAR (NR1I3 Products)
- Synonyms
- AA209988 Protein, AI551208 Protein, CAR Protein, CAR-beta Protein, Care2 Protein, ESTM32 Protein, MB67 Protein, CAR1 Protein, CXR Protein, nuclear receptor subfamily 1 group I member 3 Protein, nuclear receptor subfamily 1, group I, member 3 Protein, NR1I3 Protein, Nr1i3 Protein
- Background
- Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V- type (D1) and a C2- type (D2) Ig-like domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.
- Molecular Weight
- 24.9 kDa
- Gene ID
- 1525
- NCBI Accession
- NP_001329
- UniProt
- P78310
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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