IL2 Receptor beta Protein (His tag)
Quick Overview for IL2 Receptor beta Protein (His tag) (ABIN2566682)
Target
See all IL2 Receptor beta (IL2RB) ProteinsProtein Type
Biological Activity
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IL2 Receptor beta protein is labelled with His tag.
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Characteristics
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Measured by its ability to inhibit the IL-15-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 0. 5 - 2. 5 μg/mL in the presence of 4. 0 ng/mL of recombinant human IL-15.
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Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (His-Avi Tag)
IL2RB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (Biotin,His-Avi Tag)IL2RB Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (Biotin,His tag)IL2RB Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (His tag)IL2RB Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (Fc Tag)IL2RB Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 2 Receptor, beta (IL2RB) protein (Fc Tag)IL2RB Origin: Mouse Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Interleukin 2 Receptor, beta (IL2RB) protein (His tag)IL2RB Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) protein (His tag)IL2RB Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Application Notes
- This recombinant protein can be used for WB. For research use only.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -80 °C,-20 °C
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Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Alternative Name
- IL 2 R beta
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Background
- Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to a cytokine called IL-2. The IL-2R is made up of 3 subunits - α (CD25), β (CD122) and γ (CD132) - non-covalently associating. The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. CD122 is also known as IL2R beta, is a member of the type I cytokine receptor family. CD122 is the receptor for interleukin-2 and is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
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Molecular Weight
- 25.4 kDa
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Gene ID
- 3560
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NCBI Accession
- NM_000878
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UniProt
- P14784
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Pathways
- JAK-STAT Signaling, Growth Factor Binding
Target
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