PRDM14 Protein (DYKDDDDK Tag)
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- Target See all PRDM14 Proteins
- PRDM14 (PR Domain Containing 14 (PRDM14))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Baculovirus
- Purification tag / Conjugate
- This PRDM14 protein is labelled with DYKDDDDK Tag.
- Application
- Enzyme Activity Assay (EAA), Screening Assay (ScA)
- Characteristics
- Recombinant PRDM14 (accession number NP_078780.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 67 kDa.
- Top Product
- Discover our top product PRDM14 Protein
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PR Domain Containing 14 (PRDM14) (AA 1-571) protein (GST tag)
PRDM14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
PR Domain Containing 14 (PRDM14) (AA 1-571) protein (Strep Tag)Crystallography grade PRDM14 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
PR Domain Containing 14 (PRDM14) (AA 1-561) protein (Strep Tag)Crystallography grade PRDM14 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
- Recombinant PRDM14 is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
- Restrictions
- For Research Use only
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- Handling Advice
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -80 °C
- Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Target
- PRDM14 (PR Domain Containing 14 (PRDM14))
- Alternative Name
- PRDM14 (PRDM14 Products)
- Synonyms
- PFM11 Protein, PRDM14 Protein, prmd14 Protein, fc16b12 Protein, wu:fc16b12 Protein, PR/SET domain 14 Protein, PR domain containing 14 Protein, PRDM14 Protein, Prdm14 Protein, prdm14 Protein
- Background
- PRDM14 (PR Domain Containing 14) is a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. PRDM14 possesses histone methyltransferase activity. PRDM14 is a transcription factor that has both positive and negative roles on transcription. It is required for the maintenance of embryonic stem cell identity and the reacquisition of pluripotency in somatic cells. PRDM14 may play an essential role in germ cell development at two levels: the reacquisition of potential pluripotency, including Sox2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression. PRDM14 directly up-regulates the expression of pluripotency gene Oct4 through its proximal enhancer. PRDM14 binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3.'
- Molecular Weight
- 67 kDa
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