TBK1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TBK1 Protein (Myc-DYKDDDDK Tag) (ABIN2712379)
Target
See all TBK1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TBK1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TBK1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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TANK-Binding Kinase 1 (TBK1) (AA 1-729) protein (His tag)
custom-made TBK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TANK-Binding Kinase 1 (TBK1) (AA 1-729) protein (His tag)custom-made TBK1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TANK-Binding Kinase 1 (TBK1) (AA 1-729) protein (GST tag)TBK1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Alternative Name
- Tbk1
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Background
- The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
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Molecular Weight
- 83.5 kDa
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NCBI Accession
- NP_037386
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Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
Target
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