CREM Protein (His tag)
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- Target See all CREM Proteins
- CREM (CAMP Responsive Element Modulator (CREM))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CREM protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CREM (N-term HIS tag, transcript variant 15) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CREM Protein
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CAMP Responsive Element Modulator (CREM) (AA 1-137) protein (GST tag)
CREM Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CAMP Responsive Element Modulator (CREM) (AA 201-300) protein (GST tag)CREM Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CAMP Responsive Element Modulator (CREM) (AA 1-361) protein (His tag)Crystallography grade CREM Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
CAMP Responsive Element Modulator (CREM) (AA 1-357) protein (Strep Tag)Crystallography grade CREM Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CREM (CAMP Responsive Element Modulator (CREM))
- Alternative Name
- Crem (CREM Products)
- Synonyms
- CREM Protein, ICER Protein, CREM-2 Protein, hCREM-2 Protein, ICERI Protein, Icer Protein, cAMP responsive element modulator Protein, CREM Protein, Crem Protein
- Background
- This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
- Molecular Weight
- 29.5 kDa
- NCBI Accession
- NP_877572
- Pathways
- Retinoic Acid Receptor Signaling Pathway
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