CLP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712885

Product Details

Target: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CLP1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CLP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))

Alternative Name: Clp1 (CLP1 Products)

Synonyms: Heab Protein, RGD1307679 Protein, AI462438 Protein, ACDP1 Protein, CLP-1 Protein, CGP-39 Protein, GP-39 Protein, SPC-40 Protein, SPS-40 Protein, YKL-40 Protein, HEAB Protein, hClp1 Protein, fa28a12 Protein, wu:fa28a12 Protein, clp1 Protein, cleavage and polyadenylation factor I subunit 1 Protein, CLP1, cleavage and polyadenylation factor I subunit Protein, cyclin and CBS domain divalent metal cation transport mediator 1 Protein, chitinase 3-like 1 (cartilage glycoprotein-39) Protein, cleavage and polyadenylation factor I subunit 1 L homeolog Protein, Clp1 Protein, CNNM1 Protein, CHI3L1 Protein, CLP1 Protein, clp1 Protein, clp1.L Protein

Background: This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA cleavage complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47.5 kDa

NCBI Accession: NP_006822

Pathways: Ribonucleoprotein Complex Subunit Organization