CBLC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all CBLC Proteins
- CBLC (Cbl proto-oncogene C (CBLC))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CBLC protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CBLC / RNF57 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBLC Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CBLC (Cbl proto-oncogene C (CBLC))
- Alternative Name
- Cblc,rnf57 (CBLC Products)
- Synonyms
- CBL-3 Protein, CBL-SL Protein, RNF57 Protein, Cbl proto-oncogene C Protein, CBLC Protein, Cblc Protein
- Background
- This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Molecular Weight
- 52.3 kDa
- NCBI Accession
- NP_036248
- Pathways
- EGFR Signaling Pathway
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