IGF1R Protein (Myc-DYKDDDDK Tag)
Quick Overview for IGF1R Protein (Myc-DYKDDDDK Tag) (ABIN2713509)
Target
See all IGF1R ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This IGF1R protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human CD221 / IGF1R protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
-
Alternative Name
- Cd221,igf1r
-
Background
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
-
Molecular Weight
- 81 kDa
-
NCBI Accession
- NP_000866
-
Pathways
- RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Target
-