Selectin E/CD62e Protein (Myc-DYKDDDDK Tag)
Quick Overview for Selectin E/CD62e Protein (Myc-DYKDDDDK Tag) (ABIN2713748)
Target
See all Selectin E/CD62e (SELE) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This Selectin E/CD62e protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human CD62E / E-Selectin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Selectin E/CD62e (SELE) (Selectin E (SELE))
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Alternative Name
- Cd62e,e-Selectin
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Background
- The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
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Molecular Weight
- 64.4 kDa
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NCBI Accession
- NP_000441
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Pathways
- Thromboxane A2 Receptor Signaling
Target
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