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CD70 Protein (Myc-DYKDDDDK Tag)

This Recombinant CD70 protein is produced in HEK-293 Cells. There is 1 publication available.
Catalog No. ABIN2713767

Quick Overview for CD70 Protein (Myc-DYKDDDDK Tag) (ABIN2713767)

Target

See all CD70 Proteins
CD70 (CD70 Molecule (CD70))

Protein Type

Recombinant

Origin

  • 32
  • 10
  • 1
  • 1
  • 1
Human

Source

  • 25
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This CD70 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human CD70 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Expression System HEK-293 Cells
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Mazor, Hansen, Yang, Chowdhury, Wang, Stephens, Wu, DallAcqua: "Insights into the molecular basis of a bispecific antibody's target selectivity." in: mAbs, Vol. 7, Issue 3, pp. 461-9, (2015) (PubMed).

  • Target

    CD70 (CD70 Molecule (CD70))

    Alternative Name

    CD70

    Background

    Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. [UniProtKB/Swiss-Prot Function]

    Molecular Weight

    20.9 kDa

    NCBI Accession

    NP_001243

    Pathways

    Cancer Immune Checkpoints
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