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CENPA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

CENPA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713905
  • Target See all CENPA Proteins
    CENPA (Centromere Protein A (CENPA))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CENPA protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CENP-A (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CENPA Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CENPA (Centromere Protein A (CENPA))
    Alternative Name
    Cenp-A (CENPA Products)
    Synonyms
    CENP-A Protein, CenH3 Protein, Cenp-A Protein, cenpx Protein, cenp-a Protein, sim2 Protein, Cenp-a Protein, RGD1563607 Protein, CENPA Protein, centromere protein A Protein, centromere protein-A Protein, centromeric histone-3 like protein Protein, centromere-specific histone H3 CENP-A Protein, cenp-A Protein, centromere protein A L homeolog Protein, histone H3-like centromeric protein A Protein, CENPA Protein, Cenpa Protein, CENP-A Protein, cenpa Protein, cenp-A Protein, cnp1 Protein, HAN_3g422 Protein, Cenp-a Protein, cenpa.L Protein, CMU_016480 Protein
    Background
    Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight
    15.8 kDa
    NCBI Accession
    NP_001800
    Pathways
    Chromatin Binding, Maintenance of Protein Location
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