CHAC1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
-
- Target See all CHAC1 Proteins
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CHAC1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human CHAC1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CHAC1 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- CHAC1 (ChaC, Cation Transport Regulator Homolog 1 (CHAC1))
- Alternative Name
- Chac1 (CHAC1 Products)
- Synonyms
- 1810008K03Rik Protein, RGD1307153 Protein, ChaC glutathione specific gamma-glutamylcyclotransferase 1 Protein, ChaC, cation transport regulator 1 Protein, ChaC glutathione-specific gamma-glutamylcyclotransferase 1 Protein, CHAC1 Protein, Chac1 Protein
- Background
- This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.
- Molecular Weight
- 23.6 kDa
- NCBI Accession
- NP_001136248
-