HSD17B3 Protein (Myc-DYKDDDDK Tag)
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- Target See all HSD17B3 Proteins
- HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HSD17B3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human 17-beta-HSD3 / HSD17B3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HSD17B3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))
- Alternative Name
- 17-beta-Hsd3,hsd17b3 (HSD17B3 Products)
- Synonyms
- EDH17B3 Protein, SDR12C2 Protein, hydroxysteroid (17-beta) dehydrogenase 3 Protein, hydroxysteroid 17-beta dehydrogenase 3 Protein, Hsd17b3 Protein, HSD17B3 Protein
- Background
- This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
- Molecular Weight
- 34.3 kDa
- NCBI Accession
- NP_000188
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis
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