ABCD1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714264

Product Details

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ABCD1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ABCD1 / ALDP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Alternative Name: Abcd1,aldp (ABCD1 Products)

Synonyms: ABC42 Protein, ALD Protein, ALDP Protein, AMN Protein, RGD1562128 Protein, zgc:172102 Protein, ABCD1 Protein, Ald Protein, Aldgh Protein, ATP binding cassette subfamily D member 1 Protein, ATP-binding cassette, sub-family D (ALD), member 1 Protein, ATP-binding cassette sub-family D member 1 Protein, ATP binding cassette subfamily D member 1 L homeolog Protein, ABCD1 Protein, Abcd1 Protein, abcd1 Protein, CpipJ_CPIJ013253 Protein, VDBG_05717 Protein, abcd1.L Protein

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Molecular Weight: 82.8 kDa

NCBI Accession: NP_000024

Pathways: Monocarboxylic Acid Catabolic Process