ASIP Protein (Myc-DYKDDDDK Tag)
-
- Target See all ASIP Proteins
- ASIP (Agouti Signaling Protein (ASIP))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ASIP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Agouti-signaling protein (ASP) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ASIP Protein
-
Agouti Signaling Protein (ASIP) (AA 33-132) protein (GST tag)
ASIP Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Agouti Signaling Protein (ASIP) (AA 23-132) protein (His tag)Crystallography grade ASIP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Agouti Signaling Protein (ASIP) (AA 23-131) protein (His tag)Crystallography grade ASIP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- ASIP (Agouti Signaling Protein (ASIP))
- Alternative Name
- Agouti-Signaling Protein (Asp) (ASIP Products)
- Synonyms
- AGSW Protein, AGTI Protein, AGTIL Protein, ASP Protein, SHEP9 Protein, ASIP Protein, AA960621 Protein, AI256638 Protein, D8Ertd580e Protein, PAR-3 Protein, Par3 Protein, Pard3a Protein, agouti signaling protein Protein, par-3 family cell polarity regulator Protein, ASIP Protein, Asip Protein, asip Protein, Pard3 Protein
- Background
- In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.
- Molecular Weight
- 12 kDa
- NCBI Accession
- NP_001663
- Pathways
- Cell-Cell Junction Organization, Feeding Behaviour
-
