ARHGDIA Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714887

Product Details

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ARHGDIA protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ARHGDIA / GDIA1 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: Arhgdia,gdia1 (ARHGDIA Products)

Synonyms: GDIA1 Protein, NPHS8 Protein, RHOGDI Protein, RHOGDI-1 Protein, Bles01 Protein, zgc:55554 Protein, zgc:77681 Protein, wu:fa96g11 Protein, ARHGDIA Protein, NV15502 Protein, 5330430M07Rik Protein, Gdi-1 Protein, Rho-GDI Protein, RhoDGI Protein, RhoGDI-1 Protein, arhgdia Protein, MGC84535 Protein, gdia1 Protein, rhogdi Protein, rhogdi-1 Protein, rhogdi1 Protein, Rho GDP dissociation inhibitor alpha Protein, Rho GDP dissociation inhibitor (GDI) alpha Protein, rho GDP-dissociation inhibitor 2 Protein, Rho GDP dissociation inhibitor (GDI) alpha L homeolog Protein, ARHGDIA Protein, Arhgdia Protein, arhgdia Protein, LOC100120432 Protein, arhgdia.L Protein

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Molecular Weight: 18.7

NCBI Accession: NP_001172007

Pathways: Neurotrophin Signaling Pathway