ARHGEF11 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
-
- Target See all ARHGEF11 Proteins
- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ARHGEF11 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human ARHGEF11 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ARHGEF11 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
- Alternative Name
- Arhgef11 (ARHGEF11 Products)
- Synonyms
- ARHGEF11 Protein, GTRAP48 Protein, PDZ-RHOGEF Protein, B930073M02 Protein, E130307F09 Protein, PDZ-RhoGEF Protein, Prg Protein, RhoGEF Protein, mKIAA0380 Protein, Gtrap48 Protein, Rho guanine nucleotide exchange factor (GEF) 11 Protein, Rho guanine nucleotide exchange factor 11 Protein, rho guanine nucleotide exchange factor 11 Protein, arhgef11 Protein, ARHGEF11 Protein, Arhgef11 Protein, LOC511220 Protein
- Background
- Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
- Molecular Weight
- 172.1 kDa
- NCBI Accession
- NP_937879
- Pathways
- Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
-