ARNT2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714934

Product Details

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ARNT2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ARNT2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Alternative Name: Arnt2 (ARNT2 Products)

Synonyms: bHLHe1 Protein, Hif-2b Protein, mKIAA0307 Protein, Arnt Protein, arnt2X Protein, arnt2a Protein, chunp6921 Protein, zfARNT2 Protein, zfARNT2a Protein, zfARNT2b Protein, zfARNT2c Protein, arnt2 Protein, MGC53123 Protein, arnt.2 Protein, MGC68805 Protein, ARNT2 Protein, aryl hydrocarbon receptor nuclear translocator 2 Protein, aryl-hydrocarbon receptor nuclear translocator 2 Protein, aryl hydrocarbon receptor nuclear translocator 2 S homeolog Protein, aryl hydrocarbon receptor nuclear translocator S homeolog Protein, ARNT2 Protein, Arnt2 Protein, arnt2 Protein, arnt2.S Protein, arnt.S Protein, LOC100067423 Protein

Background: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Molecular Weight: 78.5 kDa

NCBI Accession: NP_055677

Pathways: Warburg Effect