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ACCN4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ACCN4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714987
  • Target See all ACCN4 Proteins
    ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 3
    • 2
    Human
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ACCN4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ASIC4 / ACCN4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ACCN4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
    Alternative Name
    Asic4,accn4 (ACCN4 Products)
    Synonyms
    ACCN4 Protein, BNAC4 Protein, Accn4 Protein, Spasic Protein, acid sensing ion channel subunit family member 4 S homeolog Protein, acid sensing ion channel subunit family member 4 Protein, acid-sensing (proton-gated) ion channel family member 4 Protein, asic4.S Protein, ASIC4 Protein, Asic4 Protein
    Background
    This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
    Molecular Weight
    69.9 kDa
    NCBI Accession
    NP_878267
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