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ATP2A1/SERCA1 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

ATP2A1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715042
  • Target See all ATP2A1/SERCA1 (ATP2A1) Proteins
    ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant A
    Origin
    • 5
    • 3
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This ATP2A1/SERCA1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ATP2A1 / SERCA1 (transcript variant a) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATP2A1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
    Alternative Name
    Atp2a1,serca1 (ATP2A1 Products)
    Synonyms
    cb279 Protein, serca Protein, serca1 Protein, wu:cegs655 Protein, wu:fb17h11 Protein, wu:fb19b10 Protein, zgc:92110 Protein, ATP2A1 Protein, atp2a Protein, atp2a2 Protein, atp2b Protein, ca-p60a Protein, dar Protein, serca2 Protein, SERCA1 Protein, ATP2A3 Protein, SERCA1a Protein, Serca1 Protein, ATP2A Protein, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Protein, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 Protein, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S homeolog Protein, atp2a1 Protein, ATP2A1 Protein, atp2a2.S Protein, Atp2a1 Protein
    Background
    This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
    Molecular Weight
    110.1 kDa
    NCBI Accession
    NP_775293
    Pathways
    Ribonucleoside Biosynthetic Process
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