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ATP2B4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ATP2B4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715045
  • Target See all ATP2B4 Proteins
    ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 5
    • 4
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ATP2B4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ATP2B4 / PMCA4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATP2B4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))
    Alternative Name
    Atp2b4,pmca4 (ATP2B4 Products)
    Synonyms
    ATP2B2 Protein, MXRA1 Protein, PMCA4 Protein, PMCA4b Protein, PMCA4x Protein, atp2b2 Protein, atp2b3 Protein, mxra1 Protein, pmca4 Protein, pmca4b Protein, pmca4x Protein, zgc:152801 Protein, ATP2B4 Protein, ATP2B1 Protein, Pmca4 Protein, ATPase plasma membrane Ca2+ transporting 4 Protein, ATPase, Ca++ transporting, plasma membrane 4 L homeolog Protein, ATPase, Ca++ transporting, plasma membrane 4 Protein, ATP2B4 Protein, atp2b4.L Protein, atp2b4 Protein, Atp2b4 Protein
    Background
    The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Molecular Weight
    133.8 kDa
    NCBI Accession
    NP_001675
    Pathways
    Ribonucleoside Biosynthetic Process
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