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Azurocidin Protein (His tag)

AZU1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715097
  • Target See all Azurocidin (AZU1) Proteins
    Azurocidin (AZU1) (Azurocidin 1 (AZU1))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Azurocidin protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Azurocidin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Top Product
    Discover our top product AZU1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Azurocidin (AZU1) (Azurocidin 1 (AZU1))
    Alternative Name
    Azurocidin (AZU1 Products)
    Synonyms
    AZAMP Protein, AZU Protein, CAP37 Protein, HBP Protein, HUMAZUR Protein, NAZC Protein, AZU1 Protein, Azurocidin Protein, pHBP Protein, azurocidin 1 Protein, azurocidin Protein, AZU1 Protein, CpipJ_CPIJ007384 Protein
    Background
    Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
    Molecular Weight
    25.24kD
    NCBI Accession
    NP_001691
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