BCL3 Protein (Myc-DYKDDDDK Tag)
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- Target See all BCL3 Proteins
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCL3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Bcl-3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BCL3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
- Alternative Name
- Bcl-3 (BCL3 Products)
- Synonyms
- BCL3 Protein, AI528691 Protein, Bcl-3 Protein, BCL4 Protein, D19S37 Protein, B-cell CLL/lymphoma 3 Protein, B cell leukemia/lymphoma 3 Protein, BCL3 Protein, Bcl3 Protein
- Background
- This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
- Molecular Weight
- 47.4 kDa
- NCBI Accession
- NP_005169
- Pathways
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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