EGFR Protein (Transcript Variant 3)
Quick Overview for EGFR Protein (Transcript Variant 3) (ABIN2720021)
Target
See all EGFR ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 3
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Characteristics
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- Recombinant human EGFR / ERBB1 (transcript variant 3) protein expressed in CHO cells.
- Produced with end-sequenced ORF clone
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Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Restrictions
- For Research Use only
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
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Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Alternative Name
- Egfr,erbb1
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Background
- Isoform 2 may act as an antagonist of EGF action. [UniProtKB/Swiss-Prot Function]
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Molecular Weight
- 97.5 kDa
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NCBI Accession
- NP_958440
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Pathways
- NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
Target
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