EMP2 Protein (Myc-DYKDDDDK Tag)
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- Target See all EMP2 products
- EMP2 (Epithelial Membrane Protein 2 (EMP2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EMP2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EMP2 / XMP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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Epithelial Membrane Protein 2 (EMP2) (AA 1-167) protein (GST tag)
EMP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Epithelial Membrane Protein 2 (EMP2) (AA 1-167) protein (Strep Tag)Crystallography grade EMP2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Epithelial Membrane Protein 2 (EMP2) (AA 1-172) protein (Strep Tag)Crystallography grade EMP2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EMP2 (Epithelial Membrane Protein 2 (EMP2))
- Alternative Name
- Emp2,xmp (EMP2 Products)
- Synonyms
- MGC52916 Protein, MGC130799 Protein, MGC69514 Protein, emp2 Protein, XMP Protein, epithelial membrane protein 2 L homeolog Protein, epithelial membrane protein 2 Protein, emp2.L Protein, emp2 Protein, EMP2 Protein, Emp2 Protein
- Background
- This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10).
- Molecular Weight
- 19 kDa
- NCBI Accession
- NP_001415
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