GFM2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2721847

Product Details

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GFM2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human GFM2 / EFG2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Alternative Name: Gfm2,efg2 (GFM2 Products)

Synonyms: RGD1309854 Protein, 6530419G12Rik Protein, A930009M04Rik Protein, EF-G2mt Protein, EFG2 Protein, MST027 Protein, RRF2mt Protein, mEF-G 2 Protein, si:dkey-35i22.3 Protein, zgc:153835 Protein, MRRF2 Protein, RRF2 Protein, hEFG2 Protein, ST15 Protein, G elongation factor, mitochondrial 2 Protein, G elongation factor mitochondrial 2 Protein, ribosome-releasing factor 2, mitochondrial Protein, reversion inducing cysteine rich protein with kazal motifs Protein, Gfm2 Protein, GFM2 Protein, gfm2 Protein, LOC662021 Protein, RECK Protein

Background: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA. Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 86.4 kDa

NCBI Accession: NP_115756

Pathways: Ribonucleoprotein Complex Subunit Organization