Quick Overview for IKBKB Protein (Myc-DYKDDDDK Tag) (ABIN2723357)
Target
See all IKBKB ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IKBKB protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human IKBKB / IKKB protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 1-256) protein (GST tag)
IKBKB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (AA 296-435) protein (His-IF2DI Tag)IKBKB Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
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Alternative Name
- Ikbkb,ikkb
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Background
- The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
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Molecular Weight
- 86.4 kDa
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NCBI Accession
- NP_001547
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Pathways
- NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
Target
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