IL-24 Protein (Transcript Variant 1) (His tag)
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- Target See all IL-24 (IL24) Proteins
- IL-24 (IL24) (Interleukin 24 (IL24))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- CHO Cells
- Purification tag / Conjugate
- This IL-24 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Interleukin-24 / IL24 (transcript variant 1) protein expressed in CHO cells.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Top Product
- Discover our top product IL24 Protein
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Interleukin 24 (IL24) (AA 51-206) (Active) protein (His tag)
IL24 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 24 (IL24) (AA 1-207) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 1-206) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 58-167) protein (GST tag)IL24 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 24 (IL24) (AA 52-206) protein (His tag)Crystallography grade IL24 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 24 (IL24) (AA 27-181) protein (His tag)Crystallography grade IL24 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IL-24 (IL24) (Interleukin 24 (IL24))
- Alternative Name
- Interleukin-24,il24 (IL24 Products)
- Synonyms
- C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein
- Background
- This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Molecular Weight
- 18.9 kDa
- NCBI Accession
- NP_006841
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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