KISS1 Protein (Myc-DYKDDDDK Tag)
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- Target See all KISS1 Proteins
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KISS1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KiSS-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KISS1 Protein
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KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-110) protein (His tag)
KISS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
KiSS-1 Metastasis-Suppressor (KISS1) (AA 46-145) protein (GST tag)KISS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) protein (GST tag)KISS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) protein (His tag)Crystallography grade KISS1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-130) protein (His tag)Crystallography grade KISS1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
- Alternative Name
- Kiss-1 (KISS1 Products)
- Synonyms
- HH13 Protein, KiSS-1 Protein, metastatin Protein, Eseptin Protein, KiSS-1 metastasis-suppressor Protein, KISS1 Protein, kiss1 Protein, Kiss1 Protein
- Background
- This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.
- Molecular Weight
- 14.5 kDa
- NCBI Accession
- NP_002247
- Pathways
- Positive Regulation of Peptide Hormone Secretion
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