LLGL2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2724839

Product Details

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LLGL2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human LLGL2 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: Llgl2 (LLGL2 Products)

Synonyms: lgl-2 Protein, lgl2 Protein, hgl Protein, Lgl-2 Protein, cb521 Protein, llglh2 Protein, sb:cb521 Protein, wu:fc06g08 Protein, wu:fl37c09 Protein, zgc:55895 Protein, HGL Protein, LGL2 Protein, 9130006H11Rik Protein, Llglh2 Protein, RGD1560307 Protein, LLGL2, scribble cell polarity complex component L homeolog Protein, LLGL2, scribble cell polarity complex component Protein, lethal giant larvae homolog 2 (Drosophila) Protein, llgl2.L Protein, llgl2 Protein, LLGL2 Protein, Llgl2 Protein

Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein&aposs ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 113.3 kDa

NCBI Accession: NP_001026973

Pathways: WNT Signaling