MICB Protein (Myc-DYKDDDDK Tag)
Quick Overview for MICB Protein (Myc-DYKDDDDK Tag) (ABIN2725960)
Target
See all MICB ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MICB protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human MHC class I polypeptide-related sequence B (MICB) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
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Background
- This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 42.4 kDa
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NCBI Accession
- NP_005922
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Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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