NKX2-8 Protein (Myc-DYKDDDDK Tag)
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- Target See all NKX2-8 Proteins
- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NKX2-8 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NKX2-8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NKX2-8 Protein
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NK2 Homeobox 8 (NKX2-8) (AA 1-239) protein (GST tag)
NKX2-8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
NK2 Homeobox 8 (NKX2-8) (AA 3-50) protein (GST tag)NKX2-8 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
NK2 Homeobox 8 (NKX2-8) (AA 1-239) protein (Strep Tag)Crystallography grade NKX2-8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
NK2 Homeobox 8 (NKX2-8) (AA 1-235) protein (Strep Tag)Crystallography grade NKX2-8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
- Alternative Name
- Nkx2-8 (NKX2-8 Products)
- Synonyms
- NKX2.8 Protein, NKX2H Protein, Nkx2-9 Protein, Nkx-2.9 Protein, Nkx2-8 Protein, Nkx2.9 Protein, tinman Protein, NK2 homeobox 8 Protein, NK2 homeobox 9 Protein, NKX2-8 Protein, Nkx2-9 Protein, Nkx2-8 Protein
- Background
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
- Molecular Weight
- 25.7 kDa
- NCBI Accession
- NP_055175
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