NFKBIB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all NFKBIB Proteins
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NFKBIB protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFKBIB Protein
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NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) protein (His tag)
NFKBIB Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) protein (GST tag)NFKBIB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NF-kappa-B inhibitor beta (NFKBIB) (AA 56-145) protein (GST tag)NFKBIB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
NF-kappa-B inhibitor beta (NFKBIB) (AA 1-356) protein (Strep Tag)Crystallography grade NFKBIB Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
NF-kappa-B inhibitor beta (NFKBIB) (AA 1-359) protein (Strep Tag)Crystallography grade NFKBIB Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
NF-kappa-B inhibitor beta (NFKBIB) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)NFKBIB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
- Alternative Name
- Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta (Nfkbib) (NFKBIB Products)
- Synonyms
- NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein
- Background
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 32.6 kDa
- NCBI Accession
- NP_001001716
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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