Oncostatin M Protein (OSM) (Myc-DYKDDDDK Tag)
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- Target See all Oncostatin M (OSM) Proteins
- Oncostatin M (OSM)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Oncostatin M protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Standard (STD), Antibody Production (AbP)
- Characteristics
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- Recombinant human Oncostatin-M protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product OSM Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Oncostatin M (OSM)
- Alternative Name
- Oncostatin-M (OSM Products)
- Synonyms
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- Background
- This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molecular Weight
- 25.7 kDa
- NCBI Accession
- NP_065391
- Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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