ORC6 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2727931

Product Details

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ORC6 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ORC6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Alternative Name: Orc6 (ORC6 Products)

Synonyms: Orc6l Protein, CG1584 Protein, DmORC 6 Protein, DmORC6 Protein, Dmel\\CG1584 Protein, ORC Protein, ORC6 Protein, orc6 Protein, rDmORC Protein, ORC6L Protein, ARABIDOPSIS THALIANA ORIGIN RECOGNITION COMPLEX PROTEIN 6 Protein, ATORC6 Protein, ORIGIN RECOGNITION COMPLEX SUBUNIT 6 Protein, T2P11.3 Protein, T2P11_3 Protein, origin recognition complex protein 6 Protein, DDBDRAFT_0186183 Protein, DDBDRAFT_0233113 Protein, DDB_0186183 Protein, DDB_0233113 Protein, LOC100284755 Protein, orc6l Protein, 6720420I10Rik Protein, origin recognition complex, subunit 6 Protein, Origin recognition complex subunit 6 Protein, origin recognition complex subunit 6 Protein, origin recognition complex protein 6 Protein, origin recognition complex subunit Orc6 Protein, Orc6 Protein, ORC6 Protein, CpipJ_CPIJ005016 Protein, SJAG_01267 Protein, orcF Protein, LOC100284755 Protein, orc6 Protein

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

Molecular Weight: 27.9 kDa

NCBI Accession: NP_055136

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA