PADI1 Protein (Myc-DYKDDDDK Tag)
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- Target See all PADI1 Proteins
- PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PADI1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PADI1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PADI1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PADI1 (Peptidyl Arginine Deiminase, Type I (PADI1))
- Alternative Name
- Padi1 (PADI1 Products)
- Synonyms
- HPAD10 Protein, PAD1 Protein, PDI Protein, PDI1 Protein, AV236283 Protein, Pdi1 Protein, peptidyl arginine deiminase 1 Protein, peptidyl arginine deiminase, type I Protein, PADI1 Protein, Padi1 Protein
- Background
- This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.
- Molecular Weight
- 74.5 kDa
- NCBI Accession
- NP_037490
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