PAPPA Protein (Myc-DYKDDDDK Tag)
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- Target See all PAPPA Proteins
- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PAPPA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Pappalysin-1 / PAPPA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PAPPA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
- Alternative Name
- Pappalysin-1,pappa (PAPPA Products)
- Synonyms
- 8430414N03Rik Protein, IGFBP-4ase Protein, PAG1 Protein, PAPP-A Protein, ASBABP2 Protein, DIPLA1 Protein, PAPA Protein, PAPPA1 Protein, Pappa Protein, pappalysin 1 Protein, pregnancy-associated plasma protein A Protein, PAPPA Protein, Pappa Protein, Pappa1 Protein
- Background
- This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
- Molecular Weight
- 178.6 kDa
- NCBI Accession
- NP_002572
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